XEOMIN® in Aesthetics: How Does it Work?

When you squint or frown, the muscles between your brows contract, causing the skin to furrow and fold. These lines that occur due to facial mimics are referred to as dynamic lines. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines.

Botulinum toxin type A – the active ingredient in XEOMIN® – is used in facial aesthetic treatment to treat dynamic lines like glabellar frown lines. It acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, XEOMIN® can temporarily reduce the frown lines on your forehead between your eyes.

Xeomin chemically resembles cosmetic injectables like Botoxbecause it contains incobotulinumtoxin A, a type of botulinum toxin that relaxes muscles by inhibiting the release of acetylcholine, a chemical messenger that stimulates the contraction of muscle fibers. Because release of ACh is not completely stopped, muscles will still be able to contract but not as strongly, which allows muscles to behave normally but without as much force.

How is Xeomin Different from Dysport or Botox? On the atomic level, Xeomin differs from Dysport or Botox because it does include protein additives. The benefit from not having protein additives involves patients who stop responding to Dysport or Botox treatments due to the emergence of protein antibodies in the body. Although these antibodies are harmless, they can eventually act as agents that are counteractive to the anti-wrinkling and folding ability of Botox or Dysport.

Because Xeomin does not contain protein additives, its molecules are essentially “naked”, meaning that patients will not develop antibodies to Xeomin’s anti-aging, muscle relaxing properties. Xeomin also provides additional benefits by representing a successful treatment for the reduction of hyperhidrosis, or excessive underarm and palm sweating and for decreasing the appearance of a overly “gummy” smile, in which the lips tend to rise abnormally high above the gum line when smiling.